Double Helix: Religion Requires Memory; Memory-Killing Drugs Inspire Big Questions
By Arri Eisen
May 1, 2009
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A host of experimental new drugs interfere with the process of creating memory, promising to help combat sufferers, addicts and others. But if memory is required for the creation of ethics (and religion) and indeed in the formation of who we are, what effect might these drugs have on our identities?

Magic bullet?

Surely you remember Total Recall, the hugely successful 1990 film starring California’s current governor and based on the great Philip K. Dick short story?

But what just happened when you tried to remember whether you remember it?

What if I could block that memory, or insert another one in its place (as happens in the story)?

Todd Sacktor at SUNY Downstate Medical Center is working on the most recent example of a drug that might have been plucked directly from science fiction. When he injects the drug into rats who have learned (that is, retained the memory) not to walk on a surface that gives them a mild shock, they turn right around and walk on it again.

Ethics=Memory?

I teach a class on bioethics to college students. We start the course with the simple question: What are we? Are we are genes? Our memories? A combination? It seems to me we are, in large part, our memories. Not just our individual memories, but also our cultural memories, and our species’ memories. In fact, one whole theory of the evolution of consciousness, by the engaging eccentric Julian Jaynes, posits memory as the initial font of consciousness and even of primitive religion.

Jaynes imagines a primitive tribe sitting around a fire. They have strong memories of warnings from their former leader, who recently died. It is dark, but the leader’s ideas—build a fire, stay together—still have power beyond his death. He is keeping them safe without his being present. Thus soweth the seeds of awareness and the power of things we cannot see or understand.

Whether you agree with Jaynes’ theories (which I’ve greatly simplified) or not, it’s clear that ethics—and its ritualized partner, religion—are significantly shaped and driven by memory: memories of how to do things, why we do or should do things, how those before us did them, how we felt when we did or did not do them.

As a biologist, I ask: what exactly is a memory? Whatever it is and wherever it comes from, it must eventually be stored and maintained in brain tissues, ions, genes, and proteins. And, although it remains exciting as an academic question, and entertaining as science-fiction fodder, deeper and potentially more explosive societal issues hide in the question’s broad shadow. It is these more profound issues—with a healthy dash of sheer curiosity, no doubt—that have led Sacktor and other scientists to the story. For, if we can understand, at least at a basic biological level, what a memory is:

  • Can we eliminate damaging, traumatic memories that cripple many people, including innumerable members of the military?
  • Can we preemptively prevent post-traumatic stress by not allowing certain memories to form in the first place?
  • Can we alter memories to treat damaging addictions (because, after all, is it a particular kind of memory that happens in addiction)?
  • Or even, improve human normal learning ability and capacity?

And then, the big one: if we can, should we? In the case of the military, for example, what’s the potential downside to minimizing the psychic toll of war? More generally, altering one memory probably alters others—and doesn’t altering memories alter who we are? Were? Will be?

Offloading the Pain

Yes, you might say, relieved to escape the complexities of the situation, of course we should work to understand memory and develop drugs and other therapies so we can alleviate suffering: to prevent the suicide of a soldier returning from Iraq and paralyzed by depression, or of the child who witnesses the killing of his parents in Rwanda or Chicago.

However, we’re now familiar with the reality that most every experimental drug that makes it to market (see: Ritalin) and even some that don’t (see: LSD) move from therapeutic uses to enhancement uses. But maybe that’s okay. Maybe we’re even obligated to use new drugs that ‘improve’ people if we can. Sorry; the complexities are inescapable.

In his short story “Offloading for Mrs. Schwartz,” author and scientist George Saunders brilliantly weaves these complexities into a compelling narrative. Saunders focuses on memory, but his insight resonates more broadly to the eternal conundrum of discovery: new ideas for good can almost always also be used for bad—and how you define good or bad ain’t easy.

Saunders’ protagonist is depressed and, two years later, unable to get over the untimely death of his wife just after he’d yelled something brutally bitter at her. One day, while operating a business that provides customers with temporary virtual memories he discovers serendipitously that he can offload memories from one person’s brain for the enjoyment of another. He eventually stumbles upon the answer to his own depression and heartache: erase all his memories and start over as a new person. Immediately after the erasure, he reads the note he’d written to himself just prior:

You are alone in the world... Find someone to love. Your heart has never been broken. You’ve never done anything unforgiveable or hurt anyone beyond reparation. Everyone you’ve ever loved, you’ve treated like gold.

Tags: arri eisen, drugs, experimental, george saunders, julian jaynes, lsd, memory, military, philip k dick, ptsd, research and development, ritalin

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Am I to be..

A Clockwork Orange? People were so fascinated with the 'ultra violence' of this movie they lost sight of the theme, but the moral dimensions of free will and controlling human behavior are right there. But there is no answer, which seems correct.

Messing with memory compromises Autonomy

Very interesting article – I agree that memory is indeed an essential component of ethics; even more fundamentally, I would add that it is essential for human autonomy. Without autonomy, we cannot even begin to speak about ethics.

We usually think of autonomy as accompanying aging, but only because in our world, as individuals age they also develop an experiential storehouse of cause-effect, action-consequence pairings. This internal database helps individuals assess situations, predict consequences and make conscious decisions. Its usefulness is directly proportional to its complexity, and its accessibility. Indeed, the larger and more complex the informational database, the greater the individual’s ability to navigate the external world, in part by envisioning new choices and new directions.

If information is ablated from an intricately networked experiential database, much more is lost than simply that experience. The more ablations, the less predicting power remains. The individual regresses in ability to envision new scenarios, because this ability is based on amalgamation of previous experiences. Without a conception of alternatives, one can argue that real autonomy diminishes.

To rephrase: without memory of past actions and consequences, a person loses vital decision-making capability. If one can’t remember having loved and then lost, how will one refrain from the same behaviors that resulted in the previous loss? Or in a world where every new pain can be erased, would it even matter how many repetitive losses were sustained? Simply erase the latest uncomfortable experience and start again. What impact would this have on social communities? What impact would this have on a justice-system that is based upon analyzing the past as witnessed and remembered?

And then there is always the question: who would do the erasure? How secure is the procedure? Who gains control of the lost memories? Most of us would be uncomfortable giving an external company control over the entrances and exits of our homes. Should we be any less uncomfortable giving up control over the entrances and exits of our minds?

Eternal Sunshine of the Spotless Mind and the Manchurian Candidate are two fairly recent films that explore some possible consequences of memory erasure technology. The former explores the pitfalls of individual decision-making; the second reminds us that we don’t always have the luxury of being consulted.

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